Increasing levels of atmospheric CO 2 are expected to enhance crop yields and alter soil greenhouse gas fluxes from rice paddies. While elevated CO 2 ( ) effects on CH 4 emissions from rice paddies have been studied in some detail, little is known how might affect N 2 O fluxes or yield‐scaled emissions. Here, we report on a multi‐site, multi‐year in‐situ FACE (free‐air CO 2 enrichment) study, aiming to determine N 2 O fluxes a...

Duloxetine is a clinical drug that is primarily used for treatment of depression and pain, but it has side effects of addiction and tolerance. Cytochrome P450 (CYP) is its metabolic enzyme, and the drug’s biofunction results from its neuro-protective effect in animal and cell models. We aimed to investigate the duloxetine-induced neural cytotoxicity effect and its performance in an N2a cell neurite outgrowth model. Cell death...

General anesthesia severely affects the metabolites in the brain. Glycogen, principally stored in astrocytes and providing the short-term delivery of substrates to neurons, has been implicated as an affected molecule. However, whether glycogen plays a pivotal role in modulating anesthesia–arousal remains unclear. Here, we demonstrated that isoflurane-anesthetized mice exhibited dynamic changes in the glycogen levels in various...