Purpose The purpose of this study is to outline a complete picture of Jarisch-Herxheimer reaction (JHR) in the central nervous system among HIV-negative neurosyphilis patients. Methods A prospective study cohort of 772 cases with almost all stages of neurosyphilis depicted the features of JHR including occurrence rate, risk profiles, clinical manifestations, medical management and prognosis. Results The total occurrence rate o...

Development of environment-friendly and efficient aquaculture effluent treatment system is crucial for sustainable intensification of aquaculture, in the face of the rapidly increasing environmental pressure in the mariculture industry. In this study, mariculture wastewater was treated by the anoxic-anaerobic-oxic biochemical treatment system (A 2 O system) with traditional activated sludge replaced by nitrifying bacteria, den...

The sea ice failure mode and ice force amplitude depend on the structural form at the point of interaction, but the impacts of ice load when interacting with marine engineering structures with additional attachments are not yet clear. This study conducts numerical simulations using the discrete element method to investigate the interaction between sea ice and cable pipes attached to offshore substation structures. Various oper...