Purpose Dexamethasone (DEX) is widely used in equine practice for its potent anti-inflammatory effects and diverse studies have examined its pharmacology in horses. We integrated all available pharmacokinetic (PK) and pharmacodynamic (PD) data from 12 studies to quantify DEX disposition and endocrine effects in horses. Methods DEX concentrations in blood, urine and synovial fluid, plus cortisol (CTS) and glucose (GLU) in plasm...