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Investigating the importance of B cells and antibodies during Trichuris muris infection using the IgMi mouseNARA Subscribed
The IgMi mouse has normal B cell development; its B cells express an IgM B cell receptor but cannot class switch or secrete antibody. Thus, the IgMi mouse offers a model system by which to dissect out antibody-dependent and antibody-independent B cell function. Here, we provide the first detailed characterisation of the IgMi mouse post- Trichuris muris ( T. muris ) infection, describing expulsion phenotype, cytokine production...
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