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Monitoring of Colorectal Cancer Screening Adherence Among African American Patients of North Florida Community Health CentersNARA Subscribed
In the United States, colorectal cancer (CRC) mortality rates are higher in African Americans compared to non-Hispanic whites, partly due to advanced stage cancer diagnosis. Timely CRC screening helps to increase CRC early detection and survival in this population. The objective of this monitoring study was to survey African American patients of Community Health Centers (CHC) in north Florida and to monitor CRC screening adher...
Sea cucumbers can enhance coral growth and photophysiological performance under field conditionsNARA Subscribed
Detritivorous sea cucumbers are important processors of reef sediments and have been hypothesized to enhance coral growth by altering local nutrient availability and seawater chemistry, but whether these effects translate into improved coral performance remains untested. We conducted two analogous field experiments in Mo’orea, French Polynesia, to test whether the sea cucumber Holothuria atra enhances coral growth or photosynt...
Fentanyl decreases arterial blood oxygen saturation more than furanylfentanyl in mice due to increased apneaNARA Subscribed
Rationale Fatal opioid overdoses involving synthetic opioids have increased >10-fold over the past 8 years. Fentanyl, a potent synthetic opioid acting at the mu-opioid receptor (MOR), has largely replaced heroin as the predominant illicit opioid available. Various analogs have been synthesized from the fentanyl scaffold, including 2-furanylfentanyl, one of the most trafficked analogs from 2019 to 2024. Despite its prevalence,...
Historic coral disturbance versus current coral restoration: insights from Palmyra AtollNARA Subscribed
The utility of passive vs. active coral restoration continues to be debated as reefs decline worldwide. Here, we evaluated the efficacy of coral transplantation into the degraded East and Center lagoons of Palmyra Atoll. Corals have failed to recover in these sites over the eight decades since disturbances associated with World War II, despite high coral cover elsewhere around the atoll that could theoretically provide source...
A synthesis of principles for building the social–ecological resilience and adaptive capacity of protected and conserved areasNARA Subscribed
The long‐term success of protected and conserved areas depends on their capacity to remain relevant to human society while maintaining diverse, functional ecosystems. However, despite long‐standing interest in applying complex systems approaches to foster protected area (PA) social–ecological resilience and adaptive capacity, a gap between theory and practice remains. We reviewed the evolution of overarching principles for res...
Seasonal variation in zooplankton assemblages in Ryder Bay, Adelaide Island, Antarctic PeninsulaNARA Subscribed
Seasonal and inter-annual variations in zooplankton play a vital role in marine ecosystems. In Antarctica, because of the extreme seasonality and ice extent, zooplankton studies are predominantly conducted in summer and are based offshore. Therefore the drivers of variability are poorly understood. Here, we present one of the few year-round studies of seasonality of zooplankton communities at a coastal site in Ryder Bay, Weste...
Increased benthic biodiversity and food web recovery after decommissioning of oil and gas infrastructureNARA Subscribed
There is a global increase in the decommissioning of offshore oil and gas (O&G) infrastructure at the end of its operating lifetime. However, there is strikingly limited empirical evidence for the environmental and ecological impacts of decommissioning. Here, we employed a meta‐analytical approach on an industry benthic monitoring database to investigate the benthic biodiversity and food web properties of structures sampled in...
Thierry B.R. Chopin (1959–2024) – Innovator of Modern IMTANARA Subscribed
Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of Friedreich’s AtaxiaNARA Subscribed
Nomlabofusp is a cell penetrant peptide-based recombinant fusion protein designed to enter cells and deliver human frataxin into the mitochondria of adults and children with Friedreich’s ataxia. In this article we present non-clinical studies evaluating the pharmacology of nomlabofusp, including in a murine striated muscle tissue frataxin knockout model of Friedreich’s ataxia. We demonstrate that subcutaneous administration of...
Parasites can provide valuable insights into the ecology and health of their hosts and the state of the surrounding ecosystem. In this study, we describe the helminth parasite communities infecting penguin species in Otago, New Zealand (little blue penguin, Fiordland crested penguin, Snares crested penguin, erect crested penguin and yellow-eyed penguin). We investigate differences in parasite communities among penguin species,...
Southeast Asia hosts more felid species than any other region and, although smaller (
Using Community Composition and Successional Theory to Guide Site‐Specific Coral Reef ManagementNARA Subscribed
High spatial or temporal variability in community composition makes it challenging for natural resource managers to predict ecosystem trajectories at scales relevant to management. This is commonly the case in nearshore marine environments, where the frequency and intensity of disturbance events vary at the sub‐kilometer to meter scale, creating a patchwork of successional stages within a single ecosystem. The successional sta...