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The clinical utility of polygenic risk scores in genomic medicine practices: a systematic reviewNARA Subscribed
Genomic medicine aims to improve health using the individual genomic data of people to inform care. While clinical utility of genomic medicine in many monogenic, Mendelian disorders is amply demonstrated, clinical utility is less evident in polygenic traits, e.g., coronary artery disease or breast cancer. Polygenic risk scores (PRS) are subsets of individual genotypes designed to capture heritability of common traits, and henc...
Loop‐mediated isothermal amplification (LAMP) is a novel technique for nucleic acid amplification with high specificity, sensitivity and rapidity and does not require expensive equipment or reagents. In the present study, we developed and evaluated a LAMP method for the rapid detection of Renibacterium salmoninarum causing the bacterial kidney disease in salmonids. This method was more sensitive than quantitative real‐time pol...
Collisions Between Ships and WhalesNARA Subscribed
A bstract Although collisions with motorized ships are a recognized source of whale mortality, little has been done to compile information on the frequency of their occurrence or contributing factors. We searched historical records and computerized stranding databases for evidence of ship strikes involving great whales ( i. e. , baleen whales and the sperm whale). Historical records suggest that ship strikes fatal to whales fi...
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