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Human Genetics · 2021 · Vol. 140 · Issue 8 · Springer
The extensive clinical and genetic heterogeneity of congenital limb malformation calls for comprehensive genome-wide analysis of genetic variation. Genome sequencing (GS) has the potential to identify all genetic variants. Here we aim to determine the diagnostic potential of GS as a comprehensive one-test-for-all strategy in a cohort of undiagnosed patients with congenital limb malformations. We collected 69 cases (64 trios, 1...
International Journal of Climatology · 2019 · Vol. 39 · Issue 11 · Wiley
This study presents multifractal detrended fluctuation analysis (MF‐DFA) to describe the multifractality of Standardized Precipitation Index (SPI) series from 30 meteorological subdivisions of India estimated at different aggregation timescales (3, 6 and 12 months) based on long‐term monthly rainfall data sets of 1871–2016 period. The plots of fluctuation function and generalized Hurst exponents confirmed that multifractality...