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Toxicological Evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica ProjectNARA Subscribed
There are challenges that require collaboration among researchers to ensure that tobacco harm reduction strategies are evidence-based. A key challenge is evaluating the safety of flavors in e-cigarettes. Many flavorings are deemed “generally recognized as safe” (GRAS) for ingestion, but this does not guarantee their safety when inhaled. The Replica international research group is dedicated to the replication of studies on toba...
Tendons rely on hierarchical extracellular matrix organization for proper growth and mechanical function, but the tendon-specific role of collagen XII in this process remains poorly defined. The purpose of this study was to determine how tendon-targeted loss of collagen XII influences Achilles tendon structure, mechanics, and gene expression across key stages of postnatal development. Using tendon-targeted Scx-Cre; Col12a1 flo...
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