Cardiac diseases are strongly associated with aging and pose a major threat to survival. This study evaluated the cardioprotective effects of oral eugenol and its nano-emulsion (20 mg/kg) in a D-galactose-induced aging model (300 mg/kg, i.p.) in male and female rats over 12 weeks. Particle size and zeta potential analyses confirmed the successful development of a stable, well-dispersed nano-emulsion system. At the end of treat...

Catharanthus roseus (L.) G. Don is a key medicinal plant producing pharmacologically important terpenoid indole alkaloids (TIAs). This study aimed to enhance the biosynthesis of three major TIAs; catharanthine (CAT), vincristine (VCR), and vinblastine (VBL) through a stepwise in vitro approach involving callus culture, hairy roots (HRs) induction via Agrobacterium rhizogenes , and elicitation with zinc oxide (ZnO) and chitosan...

Promoting innovation to improve both productivity and sustainability of irrigated farming systems is crucial for the first question addressed within the Sustainable Development Goals process led by the United Nations. This is a complex task that requires methods and processes which include a diversity of knowledge. For this reason, participatory approaches have been increasingly encouraged. A broad range of methods have been d...

The precise estimation of water demand at large‐scale irrigation perimeters is a key requirement for water management. Most methods for estimating water demand use biophysical models and cropping patterns but do not account for the wide range of actual farming practices. As a result, these methods only allow estimation of theoretical water demand. The objective of this study was to analyze different methods for evaluating irri...