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Springer Nature1
Journal
Familial Cancer1
Publication Year
20231
S. Intidhar Labidi-Galy results 1 · Newest (Page 1/1, per page 25)
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Author: S. Intidhar Labidi-Galy ×Clear All Filters
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Hematologic toxicities of chemotherapy in breast and ovarian cancer patients carrying BRCA1/BRCA2 germline pathogenic variants. A single center experience and review of the literatureNARA Subscribed
Familial Cancer · 2023 · Vol. 22 · Issue 3 · Springer
Ketty Hu-Heimgartner; Noémie Lang; Aurélie Ayme; Chang Ming; Jean‑Damien Combes; Victor N. Chappuis; Carla Vazquez; Alex Friedlaender; Aurélie Vuilleumier; Alexandre Bodmer; Valeria Viassolo; José L Sandoval; Pierre O. Chappuis; S. Intidhar Labidi-Galy
BRCA1 and BRCA2 play a central role in DNA repair and their germline pathogenic variants (g BRCA ) confer a high risk for developing breast and ovarian cancer. Standard chemotherapy regimens for these cancers include DNA-damaging agents. We hypothesized that gBRCA carriers might be at higher risk of developing chemotherapy-related hematologic toxicity and therapy-related myeloid neoplasms (t-MN). We conducted a retrospective s...
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