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Shoulder Kinematic and Muscle Activity Compensations to Scapular Stabilizer Weakness: An Optimal Control FrameworkNARA Subscribed
Purpose Shoulder kinematic and muscular redundancy promotes considerable variability, obscuring possible insights into neuromuscular control and compensation mechanisms for muscle weakness or fatigue. The current study harnessed recent advancements in optimal control formulations for computational musculoskeletal models to determine potential neuromuscular control strategies to compensate for isolated muscle weakness. Methods...
Effect of coastal hypoxia on bacterial diversity as elucidated through 16S rRNA amplicon sequencingOA Marine
The formation of oxygen-depleted zones in the bottom waters is one of the most widespread phenomena in coastal areas. Upwelling episodes along India’s west coast due to the southwest monsoon increase biological productivity, further lowering the dissolved oxygen in the upwelled waters, which intensifies annually between June and October. Here, we have determined the changes in the microbial community in response to the varying...
The clinical utility of polygenic risk scores in genomic medicine practices: a systematic reviewNARA Subscribed
Genomic medicine aims to improve health using the individual genomic data of people to inform care. While clinical utility of genomic medicine in many monogenic, Mendelian disorders is amply demonstrated, clinical utility is less evident in polygenic traits, e.g., coronary artery disease or breast cancer. Polygenic risk scores (PRS) are subsets of individual genotypes designed to capture heritability of common traits, and henc...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Spatial variability of microzooplankton in the central Arabian Sea during spring intermonsoonNARA Subscribed
Spatial variability of microzooplankton (MZP; organisms in size 20–200 μm) along with total heterotrophic bacteria (THB) and picophytoplankton in the upper 120‐m water column of the central Arabian Sea (AS) was studied during the spring intermonsoon period (March 2015). Six stations divided into three regions (northern, southern, and central) were sampled along 68°E transect, between 9°N and 21°N. A total of 25 species of MZP...
Changes in extreme temperature and precipitation in the Arab region: long‐term trends and variability related to ENSO and NAONARA Subscribed
A workshop was held in Casablanca, Morocco, in March 2012, to enhance knowledge of climate extremes and their changes in the Arab region. This workshop initiated intensive data compilation activities of daily observational weather station data from the Arab region. After conducting careful control processes to ensure the quality and homogeneity of the data, climate indices for extreme temperatures and precipitation were calcul...