Microplastic pollution is becoming a major issue for human health due to the recent discovery of microplastics in most ecosystems. Here, we review the sources, formation, occurrence, toxicity and remediation methods of microplastics. We distinguish ocean-based and land-based sources of microplastics. Microplastics have been found in biological samples such as faeces, sputum, saliva, blood and placenta. Cancer, intestinal, pulm...

Stroke is the leading cause of adult disability. Endogenous neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to the brain repair process. However, molecular mechanisms underlying CNS disease-induced SVZ NSPC-redirected migration to the lesion area are poorly understood. Here, we show that genetic depletion of the p75 neurotrophin receptor ( p75 NTR−/− ) in mice reduced SVZ NSPC mig...

The accuracy of gridded precipitation data depends on the availability of a uniformly spaced rain gauge network and an appropriate spatial interpolation method that considers the rainfall variability and other factors that influence the precipitation patterns in the region of interest. In the current study, conceptually superior variants of a widely used spatial interpolation algorithm, Shepard's method, are proposed, formulat...