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This study highlights the diversity and ecological importance of freshwater endophytic fungi in Ratnapura district, Sabaragamuwa Province, Sri Lanka. Freshwater plant samples were collected from Chandrika tank (Embilipitiya), a seasonal pond at Haughton Estate (Kalawana), and Thiniyamita stream (Wewelkandura). Six endophytic species were isolated associated with different freshwater plants. These endophytes comprised of four C...
Five Decades of Fungal Research in Saudi Arabia With Significance, Checklist, Current State of Diversity, and Future PrioritiesNARA Subscribed
Despite the unique and diverse landscapes of Saudi Arabia, its fungi have not been comprehensively documented. This study compiles and categorizes available records of fungi, reported from Saudi Arabia through an extensive literature review. Data were collected from various sources, including book chapters, review articles, research papers, case studies, reports, conference proceedings, abstracts, and dissertations. More than...
Therapeutic Targeting of Krüppel-Like Factor 4 and Its Pharmacological Potential in Parkinson’s Disease: a Comprehensive ReviewNARA Subscribed
Krüppel-like factor 4 (KLF4), a zinc finger transcription factor, is found in different human tissues and shows diverse regulatory activities in a cell-dependent manner. In the brain, KLF4 controls various neurophysiological and neuropathological processes, and its contribution to various neurological diseases has been widely reported. Parkinson’s disease (PD) is an age-related neurodegenerative disease that might have a conne...
Unraveling the Endocannabinoid System: Exploring Its Therapeutic Potential in Autism Spectrum DisorderNARA Subscribed
The salient features of autism spectrum disorder (ASD) encompass persistent difficulties in social communication, as well as the presence of restricted and repetitive facets of behavior, hobbies, or pursuits, which are often accompanied with cognitive limitations. Over the past few decades, a sizable number of studies have been conducted to enhance our understanding of the pathophysiology of ASD. Preclinical rat models have pr...
RecruitNet : A global database of plant recruitment networksNARA Subscribed
Plant recruitment interactions (i.e., what recruits under what) shape the composition, diversity, and structure of plant communities. Despite the huge body of knowledge on the mechanisms underlying recruitment interactions among species, we still know little about the structure of the recruitment networks emerging in ecological communities. Modeling and analyzing the community‐level structure of plant recruitment interactions...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...