S.P. Das results 284
· Newest (Page 1/12, per page 25)
Author: S.P. Das ×Clear All Filters
Search Results
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Population Genomic Structure of Sorghum Landraces Across Landscape, Environment and CultureNARA Subscribed
The spread of staple crops to diverse environments over time and their current genetic structure may reflect historical dispersal by humans, sustained human preference for particular traits and adaptation to local environments. Sorghum is a drought‐tolerant crop native to Africa cultivated by hundreds of millions of smallholders globally. Here we examined the ecological context of population‐genomic structure of 1806 sorghum l...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Understanding variation in home range size (HR) provides important insights into the underlying ecological processes driving space use. However, it remains unclear whether the interspecific allometric scaling of mammals' HR can also be consistently observed within species and for both sexes. To address this knowledge gap, we GPS‐tracked 349 resident individuals across Brazil, encompassing 18 mammal species. We estimated indivi...