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In this study, a series of novel oxadiazole-based fluorescent dyes were synthesized and thoroughly characterized through spectroscopic analysis, theoretical modeling, and application testing. The structural design incorporated donor–acceptor motifs to promote intramolecular charge transfer (ICT), resulting in strong fluorescence across the violet-to-green spectral region (363–536 nm) with large Stokes shifts. The photophysical...
Background Vascular calcification (VC) is a major predictor of cardiovascular diseases that represent the principal cause of mortality among type-2 diabetic patients. Accumulating data suggest the vital role of some microRNAs on vascular calcification as an epigenetic regulator. Thus, we assessed herein, the role of serum miR-433-3p in vascular calcification in type-2 diabetic patients. Methods Twenty healthy subjects (control...
Purpose Diet and nutrition are important for cancer prevention. To investigate associations between dietary behavior, demographics, and risk of cancer, we assessed dietary behavior and urinary concentration of gallic acid, a polyphenol with anticancer properties found in various fruits and vegetables, in racial and ethnic minorities. Methods Ninety-one (91) participants were recruited from senior centers in East Harlem, New Yo...
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