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Springer Nature1
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Metabolic Brain Disease1
Publication Year
20251
Samar Imran results 1 · Newest (Page 1/1, per page 25)
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Author: Samar Imran ×Clear All Filters
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s diseaseNARA Subscribed
Metabolic Brain Disease · 2025 · Vol. 40 · Issue 7 · Springer
Ahmad Raza; Shafaq Saleem; Samar Imran; Sarah Rahman; Muhammad Haroon; Azeen Razzaq; Ahmad Hussain; Javed Iqbal; Brijesh Sathian
Type 2 Diabetes (T2D) and Alzheimer’s Disease (AD) share common risk factors that can be seen through T2D nearly doubling an individual’s likelihood of developing AD. Some AD patients show signs of metabolic dysfunction as well. This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. One of the notable ele...
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