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NARA Subscribed1
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Springer Nature1
Journal
Human Genetics1
Publication Year
20241
Samir M. Parikh results 1 · Newest (Page 1/1, per page 25)
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Mitochondrial genetic variation and risk of chronic kidney disease and acute kidney injury in UK Biobank participantsNARA Subscribed
Human Genetics · 2024 · Vol. 143 · Issue 2 · Springer
Vasantha Jotwani; Stephanie Y. Yang; Heather Thiessen-Philbrook; Chirag R. Parikh; Ronit Katz; Gregory J. Tranah; Joachim H. Ix; Steve Cummings; Sushrut S. Waikar; Michael G. Shlipak; Mark J. Sarnak; Samir M. Parikh; Dan E. Arking
Experimental models suggest an important role for mitochondrial dysfunction in the pathogenesis of chronic kidney disease (CKD) and acute kidney injury (AKI), but little is known regarding the impact of common mitochondrial genetic variation on kidney health. We sought to evaluate associations of inherited mitochondrial DNA (mtDNA) variation with risk of CKD and AKI in a large population-based cohort. We categorized UK Biobank...
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