Neisseria gonorrhoeae remains a high-priority pathogen according to the World Health Organisation Bacterial Priority Pathogens List. In South Africa, increasing antimicrobial resistance to tetracycline, ciprofloxacin, and penicillin is limiting available treatment options for N. gonorrhoeae infections. This challenge necessitates the exploration of alternative therapeutics, with natural products representing a promising source...

Plant cell walls are composed of a heterogeneous mixture of polysaccharides that require several different enzymes to degrade. These enzymes are important for a variety of biotechnological processes, from biofuel production to food processing. Several classical mannanolytic enzyme functions of glycoside hydrolases (GH), such as β-mannanase, β-mannosidase and α-galactosidase activities, are helpful for efficient mannan hydrolys...