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Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)NARA Subscribed
Standard information reporting helps to ensure that assay conditions and data are consistently reported and to facilitate inter-laboratory comparisons. Here, we present recommendations on minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA). The TEER assay is extensively used to evaluate the health of an epithelial/endothelial cell culture model and as an indicator of...
We analysed a recently released corpus of climate-related tweets to examine the macro-level factors associated with public declarations of climate change scepticism. Analyses of over 2 million geo-located tweets in the U.S. showed that climate scepticism – and the aggressiveness of climate-related tweets – was greater in states with higher per capita carbon emissions. This pattern remained significant after controlling for pol...
A re-analysis that replicated a replication: Rejoinder toNARA Subscribed
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Design of a Drug-Eluting Subcutaneous Implant of the Antiretroviral Tenofovir Alafenamide FumarateNARA Subscribed
Purpose Sexual transmission of HIV has been clinically proven to be preventable with a once-daily oral tablet; however, missed doses dramatically increase the risk of HIV infection. Long-acting subcutaneous implants do not allow the user to miss a dose. A desirable long-acting drug-eluting implant can deliver a constant amount of drug, adjust the delivered dose, and be readily manufactured. We present a long-acting, subcutaneo...
Hispaniola is a geotectonically complex island consisting of two palaeo‐islands that docked c. 10 Ma, with a further geological boundary subdividing the southern palaeo‐island into eastern and western regions. All three regions have been isolated by marine barriers during the late Cenozoic and possess biogeographically distinct terrestrial biotas. However, there is currently little evidence to indicate whether Hispaniolan mamm...
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