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Molecular Neurobiology · 2026 · Vol. 63 · Issue 1 · Springer
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination, blood–brain barrier disruption, and leukocyte infiltration. The transmembrane glycoprotein cluster of differentiation 44 (CD44) has been implicated in neuroinflammation, but its functional role remains unclear. Here, we examined CD44 expression and function across both non–immune-mediated and immune-med...