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Springer Nature1
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Inflammation Research1
Publication Year
20261
Sanni Foster results 1 · Newest (Page 1/1, per page 25)
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Calpain inhibition by calpeptin modulates adipocyte lipid metabolism and secretome-mediated inflammatory crosstalk with hepatocytesNARA Subscribed
Inflammation Research · 2026 · Vol. 75 · Issue 1 · Springer
Johanna Matilainen; Sanni Foster; Viivi Berg; Anne-Mari Mustonen; Sanna Oikari; Kirsi Rilla; Reijo Käkelä; Sanna P. Sihvo; Petteri Nieminen
Objective Calpeptin, a calpain inhibitor with potential for treating inflammatory diseases, reduces extracellular vesicle (EV) secretion. While adipose tissue is a recognized target of calpeptin, its effects on lipid metabolism remain unknown. We investigated calpeptin’s impact on fatty acid (FA) profiles and metabolic pathways in human Simpson-Golabi-Behmel Syndrome adipocytes and their EVs. Methods Adipocytes were treated wi...
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