Continued monitoring of polychlorinated biphenyl (PCB) residues in inland watercourses contributes indirectly to Sustainable Development Goal 14 by preserving aquatic biodiversity and ecosystems. Therefore, the current work aims to monitor PCBs in water courses of Giza, Al-Qaliobiah, and Al-Gharbiah Egyptian Governorates and assess their risk using various tools. The highest water temperature was 32.2 °C et al.-Gharbiah during...

The aim of the current study is to identify the possible protective effect of rupatadine (RUP) on ovarian ischemia reperfusion (OIR) in rats. RUP was administered in the presence and absence of OIR. Thirty-two adult Wistar albino female rats were randomly arranged into four groups: Sham, RUP (6 mg/kg/day) for 14 days, OIR and OIR + RUP groups.The results demonstrated that OIR significantly lowered serum anti-mullerian hormone...

T his article is aimed at assessing the anti-fibrotic action of plant-based fabricated cerium oxide nanoparticles (CeO 2 NPs). The Carissa carandas aerial parts methanolic extract was utilized to prepare CeO 2 NPs, where the dispersal of particle size distribution and zeta potential value was 61.9 nm and − 18.94 mV, respectively, verifying the successful synthesis of CeO 2 NPs. In rats, CeO 2 NPs were intravenously injected at...

Among the chronic and progressive autoimmune disorders that primarily affect joints in the hands, wrists, and knees, rheumatoid arthritis (RA) is a highly prevalent one. A significant number of patients develop severe adverse events, display weak responses, or cannot afford long-term use of the current RA medications, requiring more efficient and safer curative alternatives. increasing evidence recommends the application of me...

This study was conducted to evaluate the impact of sodium hydrogen sulfide (NaHS) on the therapeutic efficacy of bone marrow mesenchymal stem cells (BM-MSCs) in the treatment of collagen-induced arthritis (CIA) rats. MSCs were isolated and cultured from rat bone marrow, and their characteristics were determined. The CIA model was induced in rats by intradermal injections of type II collagen on days 0 and 21. A variety of treat...

The aquatic environment has been contaminated by pyrethroids and triazole pesticide applications, which pose serious health risks to the aquatic ecosystem and human beings. Therefore, the current study aims to evaluate water quality parameters, fungal diversity, and distribution of snails and aquatic plants of certain Egyptian water courses contaminated with pyrethroids and triazole pesticides. Seasonal samples were taken thro...

Demyelination is a frequent yet crippling neurological disease associated with multiple sclerosis (MS). The cuprizone (CZ) model, which causes demyelination through oxidative stress and neuroinflammation, is a popular tool used by researchers to examine this process. The polyphenol resveratrol (RESV) has become a promising neuroprotective agent in seeking for efficient therapies. In a rat model given CZ, we created and examine...

This study evaluated the effects of dietary organic acid (OA) blend on hemato-immunological responses, reproduction capacity, gene expression, and histological features of red tilapia ( Oreochromis niloticus × O. mossambicus ) broodstock. Four diets were formulated, containing 0 (control), 2, 3, and 4 g OAs kg −1 . The diets were fed to triplicate groups ( n = 3) of red tilapia broodstock (75 ± 5.56 g( (mean ± standard deviati...

Berberine (BBN) is a naturally occurring alkaloid as a secondary metabolite in many plants and exhibits several benefits including neuroprotective activities. However, data on the neuromodulating potential of nanoformulated BBN are still lacking. In the present study, BBN loaded within iron oxide nanoparticles (BBN-IONP) were prepared and characterized by transmission electron microscopy FTIR, X-ray photoelectron spectroscopy...

The present study outlines an easy, cheap, and environmentally friendly way to make Staphylococcus aureus -mediated bimetallic silver-copper nanocomposites (Ag/Cu) that can fight cancer and germs. The gram-positive S. aureus synthesized Ag, Cu, and their bi-metallic nanocomposites extracellularly. We aimed to prepare the bimetallic nanocomposite in two different ways, and we compared them in terms of characterization and biolo...

Rationale Evidence of the effects of chronic caffeine (CAFF)-containing beverages, alone or in combination with agomelatine (AGO) or quetiapine (QUET), on electroencephalography (EEG), which is relevant to cognition, epileptogenesis, and ovarian function, remains lacking. Estrogenic, adenosinergic, and melatonergic signaling is possibly linked to the dynamics of these substances. Objectives The brain and ovarian effects of CAF...