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Spatially Modulated Irradiation Alters Extracellular Vesicle MicroRNA Cargo in Rat Glioma and Astrocyte ModelsNARA Subscribed
Spatially fractionated radiation therapy, particularly minibeam radiation therapy (MBRT), improves normal tissue sparing while maintaining tumor control compared with conventional radiotherapy (CRT). However, the mechanisms underlying these advantages remain unclear. EVs carrying miRNAs are increasingly recognized as mediators of radiation-induced intercellular communication and may contribute to non-targeted and cohort effect...
The state and fate of noble metals in bornite and digeniteNARA Subscribed
Furnace slags are potential new sources of critical metals. We undertook a micron- to nanoscale study that addresses speciation, distribution and associations of phases in air-cooled flash furnace (FF, oxidised) and electric furnace (EF, reduced) slags from the Olympic Dam mining-smelting-refinery operation. Results enable understanding of the behaviour and partitioning of critical metals between melt and cooling crystalline p...
Historical genomic variation of Eurasian otters (Lutra lutra) in Britain, from hunting trophiesNARA Subscribed
Genomic data from historical specimens can provide insights into populations and processes no longer evident from modern samples. Identifying viable sources of historical DNA is key to this. Here we aimed to explore the viability of trophy hunting paws as sources of historical DNA, and to use this data for preliminary analyses to evaluate changes in population structuring over time. We aimed to search for the presence of genom...