Sleep disturbances and Alzheimer’s disease (AD) are interconnected public health challenges. However, the underlying mechanisms of their complex relationships remain elusive. Here, we propose a hypothetical integrative, stream-like model outlining how external and internal exposome factors accelerate brain aging, thereby exacerbating circadian dysregulation, orexin-mediated hyperexcitability, metabolic imbalance, and inflammag...

Chamber-housed substations are a common substation type, essential for voltage regulation, load balancing, and fault isolation to ensure power supply grid stability and reliability. As typically ground-based structures, chamber-housed substations are vulnerable to damage from flooding. In the case of chambers constructed from plain masonry, these may be susceptible to structural damage from forces generated by flood flows. Alt...