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In Situ Evidence for Quantitative Nitrogen Fixation in a Temperate Perennial Grass EcosystemNARA Subscribed
Biological nitrogen (N) fixation is an important terrestrial ecosystem N input that occurs in both symbiotic and non-symbiotic associations with plants. Non-symbiotic nitrogen fixation (NSNF) has been documented in many places, including soils, but the magnitude of its inputs, along with drivers of NSNF rates, remains uncertain due to methodological challenges. We measured NSNF by applying a 15 N 2 tracer to field mesocosms th...
Impacts of Quaternary Climate History on the Biogeography of Specialized Butterflies in the Great Basin of North AmericaNARA Subscribed
Aim Dramatic Quaternary climate fluctuations impacted the evolutionary history and contemporary biogeography of many residents of the Great Basin Desert of western North America. This study investigates the historical biogeographic processes that shaped the contemporary distribution of genetic variation in a polytypic group of specialized butterflies that are residents of unique dune and playa habitats. Many of the subspecies...
Bottom‐tow gear fisheries (trawls and dredges) produce ~24 million mt of harvest annually, representing a globally important animal‐sourced food system. While many are currently sustainably managed, growing concern over the potential for ecosystem impacts from bottom‐tow gears has increased pressure to improve these fisheries. We assembled an international working group of > 30 contributors, including fishing industry particip...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Ensuring consistent data quality for environmental rating ecolabels with representative secondary datasetsNARA Subscribed
Purpose Environmental rating ecolabels (ERE) are developing rapidly across Europe, intending to guide sustainable purchasing choices through performance ratings derived from life cycle assessment (LCA). Integrating robust data quality methods in the LCA modelling stage is essential for accurate and comparable ratings, but challenging as ERE must be feasible to generate with reasonable effort for broad adoption. The use of seco...
Analysis of blood-based DNA methylation signatures of aging and disease progression in inflammatory bowel diseaseNARA Subscribed
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders influenced by environmental factors and characterised by a dysregulated immune response. DNA methylation (DNAm) a key epigenetic mechanism plays a role in the etiology of complex diseases like IBD. Epigenetic clocks which estimate biological aging through DNAm patterns have also been linked to various health states, including IBD. Previously, we profiled DNA...
Environmental rating ecolabels: How does product categorization affect product ratings and potential interpretation?NARA Subscribed
Environmental rating ecolabels (ERE) aim to present aggregated product environmental information to inform consumer choices. Performance ratings (e.g., A–E) are derived from life cycle assessment (LCA) results to enable comparison between products. The translation of LCA results to performance ratings requires definition of a common rating scale, either at a sector level or for subsets of products grouped by function (i.e., pr...
Predicting the progression of MCI and Alzheimer’s disease on structural brain integrity and other features with machine learningNARA Subscribed
Machine learning (ML) on structural MRI data shows high potential for classifying Alzheimer’s disease (AD) progression, but the specific contribution of brain regions, demographics, and proteinopathy remains unclear. Using Alzheimer’s Disease Neuroimaging Initiative (ADNI) data, we applied an extreme gradient-boosting algorithm and SHAP (SHapley Additive exPlanations) values to classify cognitively normal (CN) older adults, th...
The Irrawaddy dolphin ( Orcaella brevirostris ) is an endangered cetacean that ranges throughout much of Southeast Asia and lives in coastal, estuarine, and riverine habitats including three river systems: Ayeyarwady, Mekong, and Mahakam. Many populations face risks from human interference, but overall rangewide diversity and connectivity is not well‐understood. Here we sequenced 77 complete mitogenomes from across the range o...