Higenamine, a β2-agonist, has been listed as a prohibited substance by the World Anti-Doping Agency (WADA) since 2017, poses a doping risk through the use of traditional herbal formulations. In Japan, Kampo medicines, composed of multiple crude drugs, are widely used, raising concerns about the unintentional intake of banned substances. In this study, urinary excretion of higenamine was observed in mice following coclaurine ad...

The novel esterase gene lipP1 , which encodes HjEstP1, was discovered in the genome of the extremely halophilic archaeon Haloarcula japonica . A homology search and sequence alignment revealed that HjEstP1 is a member of family IV esterases with conserved GXSXG and HGGG motifs. lipP1 was expressed in its parental strain, and recombinant HjEstP1 was purified and characterized. Optimal pH and temperature of HjEstP1 were 6.0 and...

Recruitment of Japanese jack mackerel ( Trachurus japonicus ) has been decreasing continuously since 2000 in the Pacific coastal waters of Japan. The reasons and mechanisms for this phenomenon are still unclear. Particle‐tracking experiments were performed using a data assimilation model to elucidate the effect of a current system on the transportation processes of T. japonicus from the main spawning ground in the southern Eas...