The Megalocytivirus pagrus1 causes serious disease in aquaculture and is classified into three clades: infectious spleen and kidney necrosis virus (ISKNV), turbot reddish body iridovirus (TRBIV), and red sea bream iridovirus (RSIV), further classified as genotype I or II. Several recent studies have reported RSIV strains designated as mixed genotype I/II because they were assigned to different subtypes depending on the gene us...

Mutations in the OTOF gene are a common cause of hereditary hearing loss and the main cause of auditory neuropathy spectrum disorder (ANSD). Although it is reported that most of the patients with OTOF mutations have stable, congenital or prelingual onset severe-to-profound hearing loss, some patients show atypical clinical phenotypes, and the genotype–phenotype correlation in patients with OTOF mutations is not yet fully under...

The presence of fragile X mental retardation 1 ( FMR1 ) premutation has been linked to patients with a certain type of cerebellar ataxia, the fragile X-associated tremor/ataxia syndrome (FXTAS). However, its prevalence in Japan has yet to be clarified. The aim of the present study is to determine the prevalence of FXTAS in Japanese patients with cerebellar ataxia and to describe their clinical characteristics. DNA samples were...

Life history evolution spurred by post‐Pleistocene climatic change is hypothesized to be responsible for the present diversity in periodical cicadas ( Magicicada ), but the mechanism of life cycle change has been controversial. To understand the divergence process of 13‐year and 17‐year cicada life cycles, we studied genetic relationships between two synchronously emerging, parapatric 13‐year periodical cicada species in the D...