Sean Harris results 18
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The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Interplay of education and DNA methylation age on cognitive impairment: insights from the Health and Retirement StudyNARA Subscribed
Few studies have assessed the association of educational attainment on dementia and cognitive impairment through DNA methylation age acceleration, while accommodating exposure-mediator interaction effects. We evaluated the mediation role of six epigenetic clocks with dementia, cognitive impairment non-dementia, and normal cognition, while accommodating exposure-mediator interaction effects. To understand the joint association...
Morphological Analysis of a Nearshore Nourishment along the Atlantic Coast of New Jersey, USAOA Marine
Nearshore nourishment is a common coastal flood risk management technique that can be constructed beneficially by using dredged sediment from navigation channels. A nearshore nourishment project was completed during the summer of 2021 in Harvey Cedars, NJ, USA, with 67,500 m3 of dredged sediment from Barnegat Inlet placed along approximately 450 m of beach in a depth of 3–4 m. In situ instruments were installed to monitor hydr...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Drought at a coastal wetland affects refuelling and migration strategies of shorebirdsNARA Subscribed
Droughts can affect invertebrate communities in wetlands, which can have bottom-up effects on the condition and survival of top predators. Shorebirds, key predators at coastal wetlands, have experienced widespread population declines and could be negatively affected by droughts. We explored, in detail, the effects of drought on multiple aspects of shorebird stopover and migration ecology by contrasting a year with average wet/...
A new data layer provides Coastal and Marine Ecological Classification Standard (CMECS) labels for global coastal segments at 1 km or shorter resolution. These characteristics are summarized for six US Marine Biodiversity Observation Network (MBON) sites and one MBON Pole to Pole of the Americas site in Argentina. The global coastlines CMECS classifications were produced from a partitioning of a 30 m Landsat-derived shoreline...
With the accelerating pace of global change, it is imperative that we obtain rapid inventories of the status and distribution of wildlife for ecological inferences and conservation planning. To address this challenge, we launched the SNAPSHOT USA project, a collaborative survey of terrestrial wildlife populations using camera traps across the United States. For our first annual survey, we compiled data across all 50 states dur...
Over one-third of the Earth’s population resides or works within 200 km of the coast. The increasing threat of coastal hazards with predicted climate change will impact many global citizens. Coastal dune systems serve as a natural first line of defense against rising sea levels and coastal storms. This study investigated the volumetric changes of two dune systems on Isle of Palms, South Carolina, USA prior to and following Hur...
Negative frequency‐dependent selection maintains coexisting genotypes during fluctuating selectionNARA Subscribed
Natural environments are rarely static; rather selection can fluctuate on timescales ranging from hours to centuries. However, it is unclear how adaptation to fluctuating environments differs from adaptation to constant environments at the genetic level. For bacteria, one key axis of environmental variation is selection for planktonic or biofilm modes of growth. We conducted an evolution experiment with Burkholderia cenocepaci...
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