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The study investigates the susceptibility of Atlantic salmon ( Salmo salar ) and Pacific salmon species (pink salmon, Oncorhynchus gorbuscha ; coho salmon, Oncorhynchus kisutch ; and chum salmon, Oncorhynchus keta ) to the parasitic salmon lice ( Lepeophtheirus salmonis ). The research had two main objectives: to characterize the morphology of the scaly skin in four salmonid species and to compare the cellular response at the...
Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem. We argue that there is an urgent need to improve understanding of the genetic mechanisms involved, leading to the development of tools that can be applied to boost host resistance and...
Vibrio alginolyticus , a zoonotic bacterial pathogen, expresses a type III secretion system (T3SS) that is critical for pathogen virulence and disease development. In this study, the mutant HY9901 Δ araC was obtained from the laboratory and its biological characteristics were analyzed. The swimming ability of Δ araC decreased and exhibited a 2,600 times reduction in virulence to zebrafish. However, Δ araC showed no difference...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Biofloc technology (BFT) is one of the most promising technologies in global aquaculture for the purpose of improving water quality, waste treatment, and disease prevention in intensive aquaculture systems. However, characterization of the microbial species and antibiotic resistance potentially present in biofloc-based aquaculture environments is needed. In this study, we used high-throughput sequencing technology to comprehen...
Koi herpesvirus (KHV) is a highly contagious virus that causes KHV disease (KHVD) inducing high mortality in carp and koi ( Cyprinus carpio L.). In the late stage, latency occurs with very low, often non‐detectable virus concentrations, which represents a challenge for virus detection. After validation according to OIE recommendations, an antibody ELISA was established to recognize antibodies of C . carpio against KHV infectio...
Aeromonas salmonicida ( As ) is a highly heterogeneous bacterial species, and strains’ host specificity has been reported. Ballan wrasse ( Labrus bergylta Ascanius, 1767) is susceptible to atypical As (a As ) vapA type V and type VI in Scotland and Norway. Identification of the bacterium is achieved by culture and molecular techniques; however, the available methods used to distinguish the As types are costly and time‐consumin...
Novel atypical Aeromonas salmonicida bath challenge model for juvenile ballan wrasse ( Labrus bergylta, Ascanius)NARA Subscribed
Atypical Aeromonas salmonicida (a As ) is currently one of the most routinely recovered bacterial pathogens isolated during disease outbreaks in farmed cleaner fish, ballan wrasse ( Labrus bergylta , Ascanius). Vibrionaceae family bacteria have also been isolated from ballan wrasse in Scotland. This study determined the infectivity, pathogenicity and virulence of a As and Vibrionaceae isolates in juvenile farmed ballan wrasse...
Routine gill swabbing is a non‐destructive sampling method used for the downstream qPCR detection and quantitation of the pathogen Neoparamoeba perurans , a causative agent of amoebic gill disease (AGD). Three commercially available swabs were compared aiming their application for timelier AGD diagnosis (Calgiswab ® (calcium alginate fibre‐tipped), Isohelix ® DNA buccal and cotton wool‐tipped). Calcium alginate is soluble in m...
Changes in distribution, morphology and ultrastructure of chloride cell in Atlantic salmon during an AGD infectionNARA Subscribed
Amoebic gill disease (AGD) is emerging as one of the most significant health challenges affecting farmed Atlantic salmon in the marine environment. It is caused by the amphizoic amoeba Neoparamoeba perurans , with infestation of gills causing severe hyperplastic lesions, compromising overall gill integrity and function. This study used histology, transmission electron microscopy (TEM), immunohistochemistry and transcript expre...
Methacarn preserves mucus integrity and improves visualization of amoebae in gills of Atlantic salmon ( Salmo salar L.)NARA Subscribed
Two aqueous fixation methods (modified Davidson's solution and modified Davidson's solution with 2% (w/v) Alcian blue) were compared against two non‐aqueous fixation methods (methacarn solution and methacarn solution with 2% (w/v) Alcian blue) along with the standard buffered formalin fixation method to (a) improve preservation of the mucous coat on Atlantic salmon, Salmo salar L., gills and (b) to examine the interaction betw...
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