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Springer Nature1
Journal
Stem Cell Reviews and Reports1
Publication Year
20221
Sebastian Greiser results 1 · Newest (Page 1/1, per page 25)
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Extracellular Vesicles of Mesenchymal Stromal Cells Can be Taken Up by Microglial Cells and Partially Prevent the Stimulation Induced by β-amyloidNARA Subscribed
Stem Cell Reviews and Reports · 2022 · Vol. 18 · Issue 3 · Springer
Dorota Kaniowska; Kerstin Wenk; Phil Rademacher; Ronald Weiss; Claire Fabian; Isabell Schulz; Max Guthardt; Franziska Lange; Sebastian Greiser; Matthias Schmidt; Ulf-Dietrich Braumann; Frank Emmrich; Ulrike Koehl; Yarúa Jaimes
Mesenchymal stromal/stem cells (MSCs) have great capacity for immune regulation. MSCs provide protective paracrine effects, which are partially exerted by extracellular vesicles (EVs). It has been reported that MSCs-derived EVs (MSC-EVs) contain soluble factors, such as cytokines, chemokines, growth factors and even microRNAs, which confer them similar anti-inflammatory and regenerative effects to MSCs. Moreover, MSCs modulate...
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