Multi-omics data integration has been repeatedly discussed as the way forward to more comprehensively cover the molecular responses of cells or organisms to chemical exposure in systems toxicology and regulatory risk assessment. In Canzler et al. (Arch Toxicol 94(2):371–388. https://doi.org/10.1007/s00204-020-02656-y ), we reviewed the state of the art in applying multi-omics approaches in toxicological research and chemical r...

Over the past 40 years, the significance of microzooplankton grazing in oceanic carbon cycling has been highlighted with the help of dilution experiments. The ecologically relevant Western Antarctic Peninsula (WAP) ecosystem in the Southern Ocean (SO), however, has not been well studied. Here we present data from dilution experiments, performed at three stations around the northern tip of the WAP to determine grazing rates of...

In this study, the projected changes of the average monthly and annual air temperatures, precipitation amounts and De Martonne aridity index in Serbia in the 21st century are examined. For that purpose, the spatial distribution of air temperature and precipitation amount is statistically modelled using data of 64 climatologic stations and 421 precipitation stations for the period 1976–2005 using multiple linear regression. The...

Summary C4‐dicarboxylates, such as fumarate, l ‐malate and l ‐aspartate represent substrates for anaerobic growth of Escherichia coli by fumarate respiration. Here, we determined whether C4‐dicarboxylate metabolism, as well as fumarate respiration, contribute to colonization of the mammalian intestinal tract. Metabolite profiling revealed that the murine small intestine contained high and low levels of l ‐aspartate and l ‐mala...

We report the ability of an urban canopy model, coupled with a regional climate model, to simulate energy fluxes, the intra-urban variability of air temperature, urban-heat-island characteristics, indoor temperature variation, as well as anthropogenic heat emissions, in Berlin, Germany. A building energy model is implemented into the Double Canyon Effect Parametrization, which is coupled with the mesoscale climate model COSMO-...

Exposure of cells or organisms to chemicals can trigger a series of effects at the regulatory pathway level, which involve changes of levels, interactions, and feedback loops of biomolecules of different types. A single-omics technique, e.g., transcriptomics, will detect biomolecules of one type and thus can only capture changes in a small subset of the biological cascade. Therefore, although applying single-omics analyses can...

In the face of an increasing number of urban climate modelling studies performed at sub‐kilometre resolution, systematic investigations of the performance of high‐resolution urban climate simulations and their dependency on spatial resolution are still very sparse. This study investigates the impact of the scale of representation of the urban area on the urban climate simulation with a multi‐layer urban canopy model (UCM) inte...

The impact of global climate change on urban relative to rural summertime air temperatures is investigated for nine major cities in Germany, under the Representative Concentration Pathway trajectory 8.5. The analysis is based on simulations of representative summers with a regional climate model ( RCM ) in conjunction with a multilayer urban parametrization when driven by three global circulation models ( GCMs ). The GCMs are...

Summary Corrinoid‐dependent reductive dehalogenation is mediated by phylogenetically diverse anaerobic bacteria that either synthesize corrinoids de novo or are dependent on corrinoid salvaging from the environment. The tetrachloroethene ( PCE ) reductive dehalogenase ( PceA ) of the G ram‐negative E psilonproteobacterium S ulfurospirillum multivorans harbours a norpseudo‐ B 12 as corrinoid cofactor. Norpseudo‐ B 12 differs fr...