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Age and sex dependent shift in murine gut microbiome reveals pathological links to host cardiovascular and metabolic pathwaysNARA Subscribed
The gut microbiome undergoes dynamic, sex-dependent changes across the lifespan. However, comprehensive studies examining the combined effects of age and sex are limited. This study investigated both compositional and functional alterations in the gut microbiome of young (4 months, n = 14) and aged (20 months, n = 20) C57BL/6 J mice of both sexes using 16S rRNA gene (V3–V5) sequencing. Microbial community structure and predict...