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Microencapsulation of Monascus Red Pigment Using Saccharomyces cerevisiae Ghosts: Process Optimization and CharacterizationNARA Subscribed
Monascus red pigment (MRP) is a highly pigmented microbial secondary metabolite having a therapeutic potential, which can be further enhanced through incorporation into various drug carriers. In this study, MRP produced by Monascus purpureus ATCC16436 was microencapsulated using Saccharomyces cerevisiae ( S . cerevisiae ) ghosts (ScGs) as a biocarrier, resulting in an innovative bioformulation that integrates the properties of...
Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variantsNARA Subscribed
As of the 7 th of July 2024, 775,754,322 confirmed cases of COVID-19, including 7,053,902 deaths worldwide, had been reported to the WHO (World Health Organization). Nevertheless, untill the 15 th of July 2024, a total of 13,578,710,228 vaccine doses had been administered, with almost no country spared from COVID-19 attacks. The pathophysiology of this virus is complicated, and several symptoms require a deep understanding of...
Oxidative Stress and Immunopathological Alterations of Clarias gariepinus Exposed to Monocyclic Aromatic Hydrocarbons (BTX)NARA Subscribed
This study’s goal was to assess the catfish’s response to exposure to monoaromatic petroleum hydrocarbons (benzene, toluene, and xylene) and its recovery after exposure using oxidative stress, histopathological, and immunological changes as biomarkers. Four groups: one as control and other three exposed to benzene (0.762 ng/L), toluene (26.614 ng/L), and xylene (89.403 ng/L), respectively, for 30 days and then recovery period...
The potential role of insulin resistance in predicting outcome from intravenous thrombolytic therapyNARA Subscribed
Background The potential impact of insulin resistance on stroke prognosis after IV thrombolysis is poorly understood. This study aimed to assess the effect of insulin resistance and metabolic syndrome on the outcome of IV thrombolysis in non-diabetic patients with acute ischaemic stroke. Methods This prospective observational study was conducted on 70 non-diabetic acute ischaemic stroke patients who received rt-PA within 3 h o...
Haemato-biochemical, mutagenic, and histopathological changes in Oreochromis niloticus exposed to BTXNARA Subscribed
The study of the DNA damage response in erythrocytes after exposure to volatile organic compounds (VOCs) can present evidence for its potential effect as genotoxic- biomarkers for environmental pollution. Although VOCs are dangerous pollutants, still little is known about hemotoxic, cytotoxic, and genotoxic effects of such pollutants on fish. We optimized an assay method for apoptosis and DNA damage in erythrocytes of adult ti...
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