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Springer Nature1
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The Journal of Membrane Biology1
Publication Year
20241
Shamit Kumar results 1 · Newest (Page 1/1, per page 25)
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Residues of TRPM8 at the Lipid-Water-Interface have Coevolved with Cholesterol Interaction and are Relevant for Diverse Health DisordersNARA Subscribed
The Journal of Membrane Biology · 2024 · Vol. 257 · Issue 5-6 · Springer
Deep Shikha; Ritesh Dalai; Shamit Kumar; Chandan Goswami
TRPM8 is a non-selective cation channel that is expressed in several tissues and cells and also has a unique property to be activated by low-temperature. In this work, we have analyzed the conservation of amino acids that are present in the lipid-water-interface (LWI) region of TRPM8, the region which experiences a microenvironment near the membrane surface. We demonstrate that the amino acids present in the LWI region are mor...
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