Developing new chemotherapeutic agents is essential for improving cancer treatment and overcoming resistance. In this study, four novel synthetic cyanochalcone derivatives were designed, synthesized, and structurally characterized using various spectroscopic techniques. Their anticancer potential was evaluated via an MTT cytotoxicity assay against three human cancer cell lines and one normal cell line. Among the tested compoun...

An electric pulse with a sufficient amplitude can lead to electroporation of intracellular organelles. Also, the electric field can lead to electrofusion of the neighboring cells. In this paper, a finite element mathematical model was used to simulate the distribution, radius, and density of the pores. We simulated a mathematical model of the two neighbor cells to analyze the fluctuation in the electroporation parameters befor...

The rising occurrence of emerging contaminants in sludges both inhibits the anaerobic digestion of sludges and induces health issues when sludges are recycled in agriculture, calling for methods to remove contaminants. Here we review emerging pollutants in wastewater treatment plants, before and after anaerobic digestion. We present their inhibitory effects and remediation methods to alleviate inhibition. Pharmaceuticals have...