Tree growth and lifespan are key determinants of forest dynamics, and ultimately control carbon stocks. Warming and increasing CO 2 have been observed to increase growth but such increases may not result in large net biomass gains due to trade‐offs between growth and lifespan. A deeper understanding of the nature of the trade‐off and its potential spatial variation is crucial to improve predictions of the future carbon sink. T...

Clinical researches including the Mayo Anesthesia Safety in Kids (MASK) study have found that children undergoing multiple anesthesia may have a higher risk of fine motor control difficulties. However, the underlying mechanisms remain elusive. Here, we report that erythropoietin receptor (EPOR), a microglial receptor associated with phagocytic activity, was significantly downregulated in the medial prefrontal cortex of young m...

Gasdermin E (GSDME), a member of the gasdermin protein family, is associated with post-lingual hearing loss. All GSDME pathogenic mutations lead to skipping exon 8; however, the molecular mechanisms underlying hearing loss caused by GSDME mutants remain unclear. GSDME was recently identified as one of the mediators of programmed cell death, including apoptosis and pyroptosis. Therefore, in this study, we injected mice with GSD...