Current global socio-environmental changes challenge human societies and give rise to new adaptation needs also for Indigenous Peoples and Local Communities (IPLCs). Based on participatory workshops with Sámi and Finn reindeer herders we examined adaptation challenges for reindeer herding in a situation characterized by complex, intertwined and unpredictable risks framed as polycrisis. We found that increasing the possibilitie...

Purpose Meniscal calcifications are associated with meniscal degeneration and osteoarthritis (OA). However, differentiating calcification types, such as basic calcium phosphate (BCP) and calcium pyrophosphate (CPP), remains challenging in vivo . Therefore, assessing new imaging possibilities is crucial in understanding calcification pathologies and their relationship with OA. This study investigated whether dual-energy compute...

RAPGEF6 is a member of the guanine nucleotide exchange factor (GEF) subfamily that acts on Rap small GTPases and contains a Ras/Rap-associating domain. Although deficiency of this gene has previously been linked to schizophrenia, no MIM phenotype entry currently associates RAPGEF6 with a defined clinical condition. In this study, trio-based whole-exome sequencing (WES) was performed in an individual presenting with psychiatric...

Manufacturing systems face growing pressure to address circularity, environmental and social sustainability, yet existing assessment approaches remain fragmented and unevenly developed across these dimensions. Moreover, the choice and relative importance of indicators are often based on ad-hoc judgement rather than systematic empirical input from experts. This study proposes a structured, expert-informed framework for the iden...

Natural ecosystems face significant pressure from climate change, biodiversity loss, and increasing socio-economic and political stressors—all of which are exacerbated by military conflict. This paper focuses on Ukraine and examines the root causes of disturbances in the country’s forest socio-ecological systems (SES), as well as the impacts of the ongoing war, to identify recovery pathways. Using a multi-method approach, we a...

Orchidaceae, one of the largest plant families, have been predicted in several analyses to be under a higher level of threat than angiosperms as a whole. Despite this, compared to many other major groups of animals and plants, orchids are under-represented on the Red List of the International Union for the Conservation of Nature (IUCN). Since 2000, concerted efforts have led to the number of orchids on the Global Red List incr...

Cameroon Blackbelly sheep are a domestic breed of hair sheep from West/Central Africa. They are popular with small‐holder farmers in Cameroon as they are highly resilient to local environmental challenges and are prolific a‐seasonal breeders. The aim of this study was to characterise the genetics of Cameroon Blackbelly sheep in relation to global sheep populations and to investigate their relationship to Caribbean hair sheep....