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Sustainable groundwater management is key to building resilience to hydrological extremes but remains challenging in data-scarce transboundary river basins. In this study, a transboundary, collaborative, physically based groundwater modelling approach has been developed for the Limpopo River Basin (LRB), which is highly vulnerable to floods and droughts. Monitoring data and model results consistently suggest that prolonged wet...
The Effects of Land‐Use Dynamics on Avian Phylogenetic Diversity Across Island EcosystemsNARA Subscribed
Aim To test whether forest extent and recent forest‐cover change are associated with avian phylogenetic diversity and community‐level evolutionary value across islands. Location Seven islands spanning Borneo and Wallacea in the Malay Archipelago. Taxon Terrestrial birds. Methods We sampled 1410 sites (2010–2022). We calculated phylogenetic diversity (PD), mean phylogenetic distance (MPD), mean nearest taxon distance (MNTD) and...
Connectivity is a multifaceted concept that has important implications for the management and conservation of marine and freshwater fishes. We developed a conceptual framework that encompasses multiple, interrelated categories of connectedness, including landscape (e.g., structural, functional) connectivity and ecological (e.g., trophic, genetic, demographic) connectivity, that together shape the flow of organisms, energy and...
Dispersal of marine plastic litter during tropical cyclonesNARA Subscribed
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Forest conversion for agriculture is a major cause of tropical biodiversity loss, but its impacts vary with spatial scale. Higher species turnover in forests than in farmland means that land‐use change causes greater biodiversity loss at broader than at local scales, yet broad‐scale assessments are scarce. Phylogenetic diversity is increasingly prioritised in conservation to protect evolutionary history under global change, ye...
Barth syndrome (BTHS) is an X-linked recessive disorder characterized by cardiomyopathy, skeletal muscle myopathy and fatigue, growth restriction, and neutropenia. Neutropenia increases the risk of life-threatening bacterial infections, a major cause of death in individuals with BTHS. Currently, there is no curative treatment for BTHS or associated neutropenia. The development of therapeutic strategies to correct BTHS-associat...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...
Tropical Land‐Use Change Disrupts Zeta‐Diversity Across TaxaNARA Subscribed
Land‐use change causes community turnover via local extinction and colonisation of species, driving biotic homogenization or heterogenization at larger spatial scales. Quantification of these processes has focused on beta‐diversity metrics, which upweight rarity and overlook the role of widespread species. A key knowledge gap is understanding the impact of land‐use change on both rare and widespread species—zeta‐diversity—allo...
Non-serous ovarian cancer in PTEN Hamartoma Tumor Syndrome: additional evidence for increased riskNARA Subscribed
Increased hereditary cancer risk is one of the hallmarks of PTEN Hamartoma Tumor Syndrome (PHTS) which is caused by a pathogenic germline variant in PTEN . Case reports and some cohort studies have described ovarian cancer (OC) in PHTS patients. Previously, we observed an enrichment of non-serous OC in PHTS compared to sporadic cases (3% vs 1%). However, ovarian cancer is currently not considered a PHTS-related cancer. The aim...