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Experimental Brain Research · 2026 · Vol. 244 · Issue 10 · Springer
The latest hypothesis regarding the source of enhanced neural activation from resistance training is the reticulospinal rather than the corticospinal tract, based on invasive animal and emerging human data. The present study employed a six-week isometric resistance training intervention in a randomized controlled design to address this knowledge gap. Thirty-nine healthy, untrained males (age ~23 y, sustained contraction group...
Ambio · 2026 · Vol. 55 · Issue 8 · Springer
Global conservation maps often overlook community lands, impacting decision-making and reducing local agency. We focus on the high-profile and regionally important case of Massaha’s ancestral territory (Ibola Dja Bana Ba Massaha). In Gabon, the forest is largely gazetted into logging concessions and described as an Eden-like wilderness despite long-term human presence. We compare Massaha’s biocultural maps to global, colonial,...
European Journal of Applied Physiology · 2026 · Vol. 126 · Issue 3 · Springer
Purpose The acute neurophysiological responses to resistance training (RT), particularly in corticospinal and reticulospinal pathways, remain unclear. This study investigated the effects of different RT modalities on these pathways. Methods Thirty-six RT-naive participants (10 males, 2 females per group) were randomly assigned to metronome-paced RT (MP-RT), self-paced RT (SP-RT), or a control group. Cortical, corticospinal, an...
European Journal of Applied Physiology · 2025 · Vol. 125 · Issue 11 · Springer
Purpose Studies investigating neural adaptation to strength training have yet to determine the loci of previously observed improvements in motor pathway function. While transcranial magnetic stimulation (TMS) studies have typically focused on the corticospinal tract, recent evidence from primates suggests that the subcortical reticulospinal tract may be the primary candidate for adaptation. Methods: Using a cross-sectional com...
GeroScience · 2025 · Springer
Cross-education (CE), the phenomenon whereby unilateral strength training induces neuromuscular adaptations in the contralateral limb, is underpinned by distributed cortical and subcortical plasticity. This study evaluated acute neural responses to a single bout of metronome-paced unilateral strength training in younger (n = 17; 27 ± 6 years) and older adults (n = 18; 67 ± 5 years). Neurophysiological assessments included cort...
European Journal of Applied Physiology · 2025 · Vol. 125 · Issue 10 · Springer
Purpose This study compared acute neuromuscular and hormonal responses and recovery in males during resistance exercises performed in Smith machine back squat (SQ) and horizontal leg press (LP). Methods Twelve healthy, physically active men performed SQ and LP loadings consisting of 5 sets at ten-repetition maximum. Maximal bilateral isometric force and sEMG activity of quadriceps femoris over 500 ms (MIVC EMG ) in isometric l...
GeroScience · 2024 · Vol. 47 · Issue 2 · Springer
Emma Short; Ian M. Adcock; Bilal Al-Sarireh; Ann Ager; Ramzi Ajjan; Naveed Akbar; Michael A. Akeroyd; Ghada Alsaleh; Ghada Al-Sharbatee; Kambiz Alavian; Winfried Amoaku; Julie Andersen; Chrystalina Antoniades; Mark J. Arends; Sue Astley; Denize Atan; Richard Attanoos; Johannes Attems; Steve Bain; Konstantinos Balaskas; Gabriel Balmus; Manohar Bance; Thomas M. Barber; Ajoy Bardhan; Karen Barker; Peter Barnes; Gemma Basatemur; Adrian Bateman; Moises Evandro Bauer; Christopher Bellamy; Edwin van Beek; Ilaria Bellantuono; Emyr Benbow; Sunil Bhandari; Rahul Bhatnagar; Philip Bloom; Dawn Bowdish; Melissa Bowerman; Melanie Burke; Roxana Carare; Emma Victoria Carrington; Jorge Iván Castillo-Quan; Peter Clegg; James Cole; Carlo Cota; Paul Chazot; Christopher Chen; Ying Cheong; Gary Christopher; George Church; David Clancy; Paul Cool; Del Galdo; Mayank Dalakoti; Soumit Dasgupta; Colleen Deane; Devesh Dhasmana; Stefan Dojcinov; Monia Di Prete; Huaidong Du; Niharika A. Duggal; Toby Ellmers; Costanza Emanueli; Mark Emberton; Jorge D. Erusalimsky; Laurence Feldmeyer; Alexander Fleming; Karen Forbes; Thomas C. Foster; Daniela Frasca; Ian Frayling; Daniel Freedman; Tamas Fülöp; Georgina Ellison-Hughes; Gus Gazzard; Christopher George; Jesus Gil; Richard Glassock; Rob Goldin; John Green; Robyn Guymer; Hasan Haboubi; Lorna Harries; Simon Hart; Douglas Hartley; Sebri Hasaballa; Christin Henein; Maggie Helliwell; Emily Henderson; Rakesh Heer; Kristofer Holte; Iskander Idris; David Isenburg; Juulia Jylhävä; Ahmed Iqbal; Simon W. Jones; Rajesh Kalaria; Venkateswarlu Kanamarlapudi; Werner Kempf; Alexandra J. Kermack; Jemma Kerns; Albert Koulman; Adnan H. Khan; James Kinross; Katarina Klaucane; Yamini Krishna; Harinderjit Singh Gill; Edward Lakatta; Ezio Laconi; Alpar Lazar; Christiaan Leeuwenburgh; Samantha Leung; Xuan Li; Ian van der Linde; Luísa V. Lopes; Antonello Lorenzini; Andrew Lotery; Pedro Machado; Sarah Mackie; Paolo Madeddu; Andrea Maier; Krishna Mukkanna; Pinelopi Manousou; Oonagh Markey; Claudio Mauro; Barry McDonnell; Reinhold J. Medina; Soma Meran; Claudia Metzler-Baddeley; Ignor Meglinksi; Neta Milman; Christina Mitteldorf; Ruth Montgomery; Andrew Conway Morris; Beda Mühleisen; Abhik Mukherkee; Andrew Murray; Scott Nelson; Anna Nicolaou; Alexander Nirenberg; Simon Noble; Lisa S. Nolan; Meritxell Nus; Canh Van On; Victor Osei-Lah; Mandy Peffers; Antony Palmer; Donald Palmer; Laura Palmer; William Parry-Smith; Graham Pawelec; Shahaf Peleg; Ranmith Perera; Andrew Pitsillides; Christopher J. Plack; Franze Progatzsky; Sonja Pyott; Kaukab Rajput; Sameera Rashid; J. Arjuna Ratnayaka; Sudhira A. B. Ratnayake; Manuel Rodriguez-Justo; Arianna Carolina Rosa; Andrew Rule; Gareth J. Sanger; Ian Sayers; Andrew Saykin; Dinesh Selvarajah; Jaswinder Sethi; Cathy Shanahan; Shai Shen-Orr; Carl Sheridan; Paul Shiels; Kastytis Sidlauskas; Sobha Sivaprasad; Judith Sluimer; Gary Small; Peter Smith; Rebecca Smith; Sarah Snelling; Ioakim Spyridopoulos; Ramasamy Srinivasa Raghavan; David Steel; Karen P. Steel; Claire Stewart; Keeron Stone; Selvarani Subbarayan; Mark Sussman; Jonas Svensson; Vyshnavi Tadanki; Ai Lyn Tan; Rudolph E. Tanzi; Amanda Tatler; Adriana A. S. Tavares; Tengku Amatullah Madeehah Tengku Mohd; Ana Tiganescu; James Timmons; Jeremy Tree; Drupad Trivedi; Emmanuel A. Tsochatzis; Dialechti Tsimpida; Elisabeth J. Vinke; Anna Whittaker; Neeru A. Vallabh; Kristin Veighey; Zoe C. Venables; Reddy Venkat; Meike W. Vernooij; Chris Verschoor; Manlio Vinciguerra; Vesna Vukanovic; Vladyslav Vyazovskiy; James Walker; Richard Wakefield; Adam J. Watkins; Anthony Webster; Caroline Weight; Birgit Weinberger; Susan L. Whitney; Rosalind Willis; Jacek M. Witkowski; Leonard L. L. Yeo; Tham Yhi Chung; Emma Yu; Michael Zemel; Stuart Calimport; Barry Bentley
Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased health span. With advancing age, the increased prevalence of ageing-related diseases can have a significant impact on health status, functional capacity and quality of life. It is therefore vital to develop comprehensive classification and staging systems for ageing-related pathologies, diseases and syndrom...
European Journal of Applied Physiology · 2024 · Vol. 124 · Issue 7 · Springer
Introduction Strength training mitigates the age-related decline in strength and muscle activation but limited evidence exists on specific motor pathway adaptations. Methods Eleven young (22–34 years) and ten older (66–80 years) adults underwent five testing sessions where lumbar-evoked potentials (LEPs) and motor-evoked potentials (MEPs) were measured during 20 and 60% of maximum voluntary contraction (MVC). Ten stimulations,...
European Journal of Applied Physiology · 2024 · Vol. 124 · Issue 7 · Springer
Purpose This study determined the effects of a 2-week step-reduction period followed by 4-week exercise rehabilitation on physical function, body composition, and metabolic health in 70–80-year-olds asymptomatic for injury/illness. Methods A parallel-group randomized controlled trial (ENDURE-study, NCT04997447) was used, where 66 older adults (79% female) were randomized to either intervention or control group. The interventio...
European Journal of Applied Physiology · 2024 · Vol. 124 · Issue 5 · Springer
Purpose Reduced spinal excitability during the transcranial magnetic stimulation (TMS) silent period (SP) has recently been shown to last longer than previously thought in the upper limbs, as assessed via spinal electrical stimulation. Further, there is reason to expect that contraction intensity affects the duration of the reduced spinal excitability. Methods This study investigated spinal excitability at different time delay...