The microtubule-associated protein tau plays a central role in neurodegenerative diseases, called tauopathies, but the mechanism involved remains incompletely understood. Here, we used Saccharomyces cerevisiae as a model system to investigate the consequences of expressing the shortest human tau isoform 0N3R. After transfected, we detected widespread cellular distribution of tau and phosphorylation at key pathological residues...

The aim of this work was to synthesize all the data obtained over the last four decades by the various researchers who have formed part of the multidisciplinary Jurassic research group founded by Professor Antonio Goy. This is, therefore, a review that seeks to integrate data from various studies on different fossil groups in the Iberian Peninsula during the transition from the Early to the Middle Jurassic. The boundary betwee...