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Springer Nature1
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JBIC Journal of Biological Inorganic Chemistry1
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20251
Spenser Stone results 1 · Newest (Page 1/1, per page 25)
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Author: Spenser Stone ×Clear All Filters
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Biochemical characterization of the self-sacrificing p-aminobenzoate synthase from Nitrosomonas europaea reveals key residues involved in selecting a Fe/Fe or Mn/Fe cofactorNARA Subscribed
JBIC Journal of Biological Inorganic Chemistry · 2025 · Vol. 30 · Issue 3 · Springer
Spenser Stone; Logan Peters; Charlotte Fricke; W. Keith Ray; Kylie D. Allen
A noncanonical route for p -aminobenzoate (pABA) biosynthesis in select bacteria utilizes a novel self-sacrificing heme oxygenase-like domain-containing oxidase/oxygenase (HDO) superfamily member. The recently characterized self-sacrificing pABA synthase from Chlamydia trachomatis (“CADD”) requires manganese and likely employs a heterobimetallic Mn/Fe cofactor. A conserved active site tyrosine residue is cleaved from the prote...
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