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Bundesweite Entwicklung der Grundwasserstände seit 1991: Langzeittrends, Variabilität und Auswirkungen der jüngsten TrockenphaseNARA Subscribed
Zusammenfassung Die Studie untersucht die Entwicklung der Grundwasserstände in Deutschland anhand von 5844 Messstellen sowie deren Reaktionsdynamik gegenüber klimatologischen Antrieben im Referenzzeitraum 1991–2020. Zusätzlich wird die Entwicklung seit 2018 im Kontext der außergewöhnlichen Dürreperiode betrachtet, um die Reaktionsfähigkeit und Vulnerabilität der Grundwassersysteme gegenüber extremen klimatischen Bedingungen zu...
Signatures of Polar Vortex Weakening in the MLTI: A ReviewNARA Subscribed
This paper is a collaborative effort that originated at the International Space Science Institute Workshop on “Physical links between Weather and Climate in Space and the Lower Atmosphere” held 22–26 January 2024. Many scientists attended that workshop and contributed their expertise related to polar vortex impacts on upper atmosphere variability. This paper summarizes well-known and newly reported signatures of polar vortex w...
Occurrence and origin of thallium in mineral and thermal waters from the northern Upper Rhine Graben and adjacent regions, GermanyNARA Subscribed
Although thallium is a widespread and highly toxic element, it is rarely investigated in environmental chemistry due to its typically low concentrations in water. Consequently, little is known about the occurrence of thallium in groundwater and its origin. Here we show that high thallium concentrations of 5 up to 99 µg/l occur in Hesse exclusively in Na-Cl-waters and are locally clustered within the Taunus Border Zone. These v...
The Felbertal tungsten deposit is the only economic scheelite mine in Europe, yet its genesis is not fully understood. It has been argued recently that the formation of the deposit is most likely related to granitic intrusions of Variscan age, contrasting a previously suggested syn-depositional stratabound origin of Early Cambrian age. Solving this controversy remains challenging due to the polymetamorphic evolution of the dep...
No general support for functional diversity enhancing resilience across terrestrial plant communitiesNARA Subscribed
Aim Understanding the mechanisms promoting resilience in plant communities is crucial in times of increasing disturbance and global environmental change. Here, we present the first meta‐analysis evaluating the relationship between functional diversity and resilience of plant communities. Specifically, we tested whether the resilience of plant communities is positively correlated with interspecific trait variation (following th...
Objectives Current research suggests static stretch-induced maximal strength increases and muscle hypertrophy with potential to substitute resistance-training routines. However, most studies investigated the plantar flexors. This study explored the effects of a static stretching program on maximal strength, hypertrophy and flexibility of the pectoralis major and compared the effects with those of traditional resistance trainin...
Standards of NGS Data Sharing and Analysis in Ataxias: Recommendations by the NGS Working Group of the Ataxia Global InitiativeNARA Subscribed
The Ataxia Global Initiative (AGI) is a worldwide multi-stakeholder research platform to systematically enhance trial-readiness in degenerative ataxias. The next-generation sequencing (NGS) working group of the AGI aims to improve methods, platforms, and international standards for ataxia NGS analysis and data sharing, ultimately allowing to increase the number of genetically ataxia patients amenable for natural history and tr...
Soil–plant interactions modulated water availability of Swiss forests during the 2015 and 2018 droughtsNARA Subscribed
Central Europe has been experiencing unprecedented droughts during the last decades, stressing the decrease in tree water availability. However, the assessment of physiological drought stress is challenging, and feedback between soil and vegetation is often omitted because of scarce belowground data. Here we aimed to model Swiss forests' water availability during the 2015 and 2018 droughts by implementing the mechanistic soil‐...
Global maps of soil temperatureNARA Subscribed
Research in global change ecology relies heavily on global climatic grids derived from estimates of air temperature in open areas at around 2 m above the ground. These climatic grids do not reflect conditions below vegetation canopies and near the ground surface, where critical ecosystem functions occur and most terrestrial species reside. Here, we provide global maps of soil temperature and bioclimatic variables at a 1‐km 2 r...
The β-Secretase Substrate Seizure 6–Like Protein (SEZ6L) Controls Motor Functions in MiceNARA Subscribed
The membrane protein seizure 6–like (SEZ6L) is a neuronal substrate of the Alzheimer’s disease protease BACE1, and little is known about its physiological function in the nervous system. Here, we show that SEZ6L constitutive knockout mice display motor phenotypes in adulthood, including changes in gait and decreased motor coordination. Additionally, SEZ6L knockout mice displayed increased anxiety-like behaviour, although spati...
Neuroinflammation within the superficial dorsal horn (SDH) of the spinal cord induces inflammatory pain with symptoms of hyperalgesia and allodynia. Glial activation and production of inflammatory mediators (e.g. cytokines) is associated with modulation of nociceptive signalling. In this context, medicinal signalling cells, e.g. obtained from adipose tissue (AdMSCs), gained attention due to their capacity to modulate the infla...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
The highly conserved YrdC domain-containing protein (YRDC) interacts with the well-described KEOPS complex, regulating specific tRNA modifications to ensure accurate protein synthesis. Previous studies have linked the KEOPS complex to a role in promoting telomere maintenance and controlling genome integrity. Here, we report on a newborn with a severe neonatal progeroid phenotype including generalized loss of subcutaneous fat,...
sPlotOpen – An environmentally balanced, open‐access, global dataset of vegetation plotsNARA Subscribed
Motivation Assessing biodiversity status and trends in plant communities is critical for understanding, quantifying and predicting the effects of global change on ecosystems. Vegetation plots record the occurrence or abundance of all plant species co‐occurring within delimited local areas. This allows species absences to be inferred, information seldom provided by existing global plant datasets. Although many vegetation plots...
Spatial population genomics of a recent mosquito invasionNARA Subscribed
Population genomic approaches can characterize dispersal across a single generation through to many generations in the past, bridging the gap between individual movement and intergenerational gene flow. These approaches are particularly useful when investigating dispersal in recently altered systems, where they provide a way of inferring long‐distance dispersal between newly established populations and their interactions with...
TRY plant trait database – enhanced coverage and open accessNARA Subscribed
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodivers...