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Contrasting the genetic architecture of cardiac glutathione against other organs: unveiling a unique tissue-specific locusNARA Subscribed
Glutathione is a ubiquitous antioxidant with critical roles in xenobiotic clearance and aerobic metabolism. Reduced glutathione (GSH) is converted to its oxidized counterpart, GSSG, in the process of neutralizing free radicals and maintaining biochemical homeostasis. An imbalance between free radical generation and antioxidant protection leads to oxidative stress and diminished GSH concentrations. Polymorphisms in GSH synthesi...
Modeling air temperature from snow-buried sensors to refine multi-decadal warming trends in Great Basin National Park, NV, USANARA Subscribed
Collecting reliable meteorological data in mountain environments is difficult because harsh conditions, complex terrain, and limited access disrupt long-term observations. In the Snake Range, Nevada, snow cover of low-cost temperature and humidity sensors creates winter gaps in near-surface air temperature records. To address this challenge, we developed three Random Forest Regression models to predict 2-m daily maximum, mean,...
A salinity gradient mediates plant diversity–function–stability relationships across a coastal marsh landscapeNARA Subscribed
Ecosystem function and stability are often positively related to species richness in experiments, but in nature, abiotic gradients may over‐ride or obscure the effects of richness on function and stability. In addition, community stability may be driven by distinct mechanisms along diversity or abiotic gradients and exhibit different responses to differing degrees of variability in an abiotic condition. We explored relationshi...
Understanding how marine species tolerate ocean acidification (OA) is critical for predicting biological responses to ocean change, as well as impacts on the ecosystems and industries that rely upon them. Snow crab ( Chionoecetes opilio ) are both a major fishery resource in the Bering Sea and an important component of high-latitude marine food webs. Experimental work suggests that snow crab are relatively tolerant of OA, but...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...