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NARA Subscribed1
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Springer Nature1
Journal
Drug Delivery and Translational Research1
Publication Year
20261
Stuart Turville results 1 · Newest (Page 1/1, per page 25)
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Comparative analysis of clinically approved lipid nanoparticles for intranasal siRNA delivery against SARS-CoV-2NARA Subscribed
Drug Delivery and Translational Research · 2026 · Springer
Yuan Zhang; Matt D. Johansen; Scott Ledger; Rebecca Shipley; Guanshu Zhao; Ernest Moles; Stuart Turville; Pall Thordarson; Philip M. Hansbro; Maria Kavallaris; Anthony D. Kelleher; Chantelle L. Ahlenstiel
SARS-CoV-2 continues to circulate globally, with persistent hospitalizations, despite a successful global vaccination strategy. We have developed highly conserved, antiviral short interfering (si)RNA and demonstrated in vivo antiviral efficacy following intranasal treatment of mice with naked siRNA. To enhance antiviral efficacy and siRNA protection, in this study we investigated the use of LNP packaging to improve delivery an...
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