Immunodeficient mouse models are invaluable tools for preclinical research, particularly for cancer therapies and studies of the human immune system. Notably, strains with combined Prkdc (scid) and Il2rg (null) mutations—such as NOG and NSG mice— are widely used due to their profound immunodeficiency, allowing efficient engraftment of various human cells. However, these models were generated by disrupting the Il2rg gene throug...

Low flow projections in response to global warming and the uncertainty decomposition into different components are performed with the focus on the Chungju basin, South Korea. Four downscaled climate simulations, two bias correction methods, and two hydrological models with two different potential evapotranspiration computation methods are applied to constitute the 32 ensemble members (4 × 2 × 4) of low flows projections. An an...