This study evaluates the hydrogeochemical characteristics, heavy metal (HM) contamination, irrigation suitability, and associated human health risks of surface water in an industrial area affected by dye-manufacturing activities in West Bengal, India. A total of 30 surface water collected in triplicate were analysed. Major ions were determined using standard American Public Health Association (APHA) methods, HMs were quantifie...

The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of orally administered drugs. Within the pharmaceutical industry, significant resources are invested to predict and characterize a clinically relevant food effect. Here, the predictive performance of physiologically based pharmacokinetic (PBPK) food effect models was assessed via de novo mechanistic absorption models...