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Stem Cell Reviews and Reports · 2024 · Vol. 20 · Issue 7 · Springer
Dysregulated progenitor cell populations may contribute to poor placental development and placental insufficiency pathogenesis. Side-population cells possess progenitor properties. Recent human trophoblast side-population isolation identified enrichment of 8 specific genes ( CXCL8, ELL2, GATA6, HK2, HLA-DPB1, INTS6, SERPINE3 and UPP1 ) (Gamage et al. 2020, Stem Cell Rev Rep ). We characterised these trophoblast side-population...