Lipid nanoparticle-messenger RNA (LNP-mRNA) drug products are a growing class of drug modalities. The unique composition of these drug products requires multiple measurements to account for the different components of these drug modalities. Pharmacokinetic (PK) measurements include measurement of the encapsulated mRNA and components of the LNP in circulation to understand the effectiveness of the therapeutic mRNA. The PK measu...

Post-Hurricane Sandy research has improved our understanding of coastal resilience during major storm events, accelerated sea level rise, and other climate-related factors, helping to enhance science-based decision-making, restoration, and management of coastal systems. The central question this special section examines is: “looking across the breadth of research, natural resource management actions and restoration projects po...