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Combined family-based association and linkage analyses in families affected by attention-deficit hyperactivity disorderNARA Subscribed
Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent and heritable of neurodevelopmental disorders. To characterize the genetic variants contributing to this heritability, we studied families with members affected by ADHD. Genome-wide array data were obtained on two cohorts: NHGRI Family Cohort (359 nuclear families,1538 individuals) and NCR Family Cohort (25 multigenerational and 132 nuclear families,...
Consistent carbon isotope ordering of cyanobacterial lipidsNARA Subscribed
Impacts of Ocean Acidification on Reproduction and Early Life Development in Marine Teleost Fish—A SynthesisNARA Subscribed
Ocean acidification (OA) remains a major and underexplored threat to marine fishes, particularly regarding reproductive physiology and early life stages (ELS). Although research over the past 15 years has documented diverse OA effects, substantial knowledge gaps persist. Most studies focussed on a limited set of species from North America and Europe, leaving broad uncertainty across phylogenetic groups, geographic regions and...
Pacific white shrimp ( Litopenaeus vannamei ) are among the most important aquaculture species but are highly susceptible to Vibrio infections. Novel disease management strategies are necessary. Previous studies have reported that peracetic acid (PAA) is an effective disinfectant, but its application in shrimp aquaculture remains underexplored. This study aimed to determine the median lethal concentration (LC 50 ) of PAA at tw...
Spatial Phylogenetic and Functional Diversity in Africa—A Case Study of the Cyperaceae (Poales)NARA Subscribed
Aim Understanding the mechanisms that influence the patterns of diversification and spatiotemporal distribution of biodiversity requires integrating species, functional and phylogenetic data. In this study, we assembled, generated and integrated trait data of native plants in Cyperaceae across Africa with their known occurrences and a pruned phylogeny to map the centres of diversity and diversification in Africa. Location Afri...
Knowledge of the dietary composition of Atlantic marlins, especially for recently acknowledged species such as roundscale spearfish ( Tetrapturus georgii ), is limited, as sample access is constrained by international quotas and intermittent landing rates. A series of annual offshore recreational fishing tournaments target Atlantic blue marlin ( Makaira nigricans ), white marlin ( Kajikia albida ) and roundscale spearfish on t...
Psychometric framework for coexistence with large carnivoresNARA Subscribed
Human–carnivore coexistence is essential for biodiversity conservation, yet measuring the attitudes and behaviors that support it remains methodologically challenging. We developed psychometric scales to assess willingness to coexist with carnivores and the underlying beliefs of this coexistence through an iterative expert elicitation process grounded in risk perception theory and moral psychology to ensure strong content vali...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...