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Continuous Distillation for Drug Substance ManufacturingNARA Subscribed
Purpose Continuous distillation is widely used in the commodity and petrochemical industry to purify fine chemicals on massive industrial scales; however, this key separation strategy is largely unused within the pharmaceutical industry. This article investigates the development of a pilot-scale continuous distillation system for in-line removal of an excess amine reactant ( i.e. , tert-butylamine) when incorporated within an...
Stony coral tissue loss disease (SCTLD) has caused unprecedented coral mortality across Florida’s Coral Reef (FCR) since 2014, raising concerns about whether coral restoration can succeed under chronic disease conditions and whether outplanting activities may increase disease transmission risk. As the disease transitioned from epizootic outbreak to enzootic persistence, we conducted a large-scale experimental outplanting to as...
Unprecedented Burning in Tropical Peatlands During the 20th Century Compared to the Previous Two MillenniaNARA Subscribed
Tropical peatland wildfire incidence has risen in recent decades, driven by drainage for land use and intensified by severe droughts with global climate change. These disturbances have altered vegetation structure, disrupted ecosystem functioning, and increased carbon emissions, particularly in Southeast Asia. However, the long‐term history and characteristics of wildfires in tropical peatlands remain largely unknown. Here, we...
N 2 O emissions by nitrifiers are often estimated using selective inhibitors, such as 1‐alkynes. However, the effects of these inhibitors on anaerobic ammonium‐oxidising (anammox) bacteria are largely unknown. In this study, we assessed the inhibitory effect of linear and aromatic alkynes on anammox activity and identified their target enzyme. ‘ Candidatus Kuenenia stuttgartiensis’ biomass and constructed wetland soil samples...
Nutrient availability modulates impacts of short‐term shifts in temperature and grazing on phytoplankton composition and size structureNARA Subscribed
The significant contribution of phytoplankton to global primary production is regulated by several abiotic and biotic factors, which are often difficult to account for in natural systems. To address these challenges, we perturbed a summer plankton community from Narragansett Bay, Rhode Island, USA, by manipulating the temperature and nutrient conditions in a controlled short‐term incubation experiment and tracked changes in ph...
Host‐microbiome interactions shape key physiological processes, including bioenergetics, neurodevelopment and xenobiotic metabolism, and strongly influence the ecological fitness of the host. However, our understanding of host‐microbiome interactions is primarily derived from post‐embryonic free‐living life stages, when the organism is in direct contact with microbes. Whether environmental microbial communities influence embry...
Warm‐Loving Species Perform Well Under Limiting Resources: Trait Combinations for Future ClimateNARA Subscribed
Ecosystems are warming alongside shifts in other abiotic factors, leading to interactive effects on populations and communities. This underscores the importance of studying how organisms respond to multiple environmental changes simultaneously. In pelagic ecosystems, as surface waters warm, longer and stronger periods of thermal stratification lead to changes in resource (light and nutrient) availability. We investigate the co...